GHK-Cu: The Peptide with Powerful Regenerative Benefits

GHK-Cu — often called copper peptide or Copper Tripeptide-1 — is a small, naturally occurring peptide that has attracted attention for its regenerative, anti-aging, and reparative effects on skin, hair, and tissue. Below we summarise the science-backed uses, practical applications, and safety considerations.

What is GHK-Cu?

GHK-Cu is a tripeptide (glycyl-L-histidyl-L-lysine) that binds copper ions. It occurs naturally in human fluids and tissues and is involved in biological processes that support tissue repair and cell health.

Key benefits & biological effects

  • Skin regeneration & anti-aging: GHK-Cu has been shown to promote collagen, elastin and glycosaminoglycan production, which can improve skin firmness, texture and reduce the appearance of fine lines and wrinkles.
  • Wound healing & tissue repair: It supports cell migration and angiogenesis (blood vessel formation), helping to accelerate healing of cuts, minor burns and scars.
  • Anti-inflammatory effects: GHK-Cu can modulate inflammatory pathways, which may reduce redness and support recovery.
  • Hair growth support: Topical or targeted formulations have been associated with improved hair follicle activity and healthier scalp environment.
  • Antioxidant and protective actions: It helps protect cells from oxidative stress and can positively affect gene expression related to tissue remodelling.

Note: this article is informational and not medical advice. For treatment of wounds, injuries or health conditions consult a qualified healthcare professional.


Frequently asked questions

Is GHK-Cu safe to use on sensitive skin?
Many people tolerate GHK-Cu well, but sensitivity varies. Patch testing and starting with lower concentration products is advised.
Can I use GHK-Cu with vitamin C or retinoids?
GHK-Cu can be combined with many active ingredients, but because strong actives can irritate, introduce combinations gradually and follow product guidance or a clinician’s advice.
How long until I see results?
Visible improvements in skin texture or hydration may appear in weeks, while structural changes like collagen increase take longer (months) and depend on formulation and consistency of use.
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