CJC-1295 DAC – 2MG: Benefits, Dosage, Usage, and Scientific Backing
Share
What is CJC-1295 DAC?
CJC-1295 with DAC (Drug Affinity Complex) is a synthetic peptide developed to enhance growth hormone (GH) secretion by mimicking the action of Growth Hormone-Releasing Hormone (GHRH). Originally developed by ConjuChem Biotechnologies, this long-acting GHRH analog significantly increases both growth hormone and insulin-like growth factor 1 (IGF-1) levels in the body, making it an appealing option in sports performance, anti-aging, and wellness communities.
The addition of DAC extends the peptide’s half-life to approximately 8–10 days, allowing for less frequent dosing and more stable GH release patterns compared to CJC-1295 without DAC or other GHRH analogues like Sermorelin1.
Benefits of CJC-1295 DAC
1. Increased Growth Hormone and IGF-1 Secretion
CJC-1295 DAC stimulates the pituitary gland to produce more GH. Elevated GH levels lead to increased IGF-1 production in the liver, a key hormone involved in muscle growth, fat metabolism, and cell regeneration2.
Study: A clinical trial by Teichman et al. (2006) demonstrated that a single dose of CJC-1295 increased GH secretion by 2–10 fold for up to 6 days and IGF-1 levels for up to 14 days3.
2. Enhanced Muscle Growth and Recovery
By promoting protein synthesis and supporting muscle cell growth via IGF-1, CJC-1295 DAC is commonly used for hypertrophy and muscle recovery after intense training sessions.
3. Fat Loss and Improved Body Composition
Growth hormone is well known for its lipolytic (fat-burning) effects. Users often report significant reduction in body fat, particularly stubborn visceral fat, alongside increases in lean muscle mass.
4. Anti-Aging Effects
GH and IGF-1 are linked to skin health, joint support, and improved sleep quality, making CJC-1295 DAC a sought-after peptide in anti-aging and longevity protocols.
5. Improved Sleep Quality
Anecdotal and clinical reports suggest improved REM sleep cycles, likely due to GH's involvement in restorative sleep, which supports mental clarity, energy, and physical recovery4.
How to Take CJC-1295 DAC – 2MG
Dosage Guidelines
Typical Dose: 2mg per injection
Frequency: Once every 5–7 days (due to the extended half-life)
Route: Subcutaneous injection (into fatty tissue, such as the abdomen)
The long-acting nature of DAC means frequent daily injections are not required, unlike GHRH analogues without DAC.
Best Time to Take
The ideal time to take CJC-1295 DAC is:
Before bed – to coincide with natural GH pulses and enhance restorative sleep
Alternatively, post-workout – to aid recovery and muscle repair
Avoid taking it close to meals high in carbohydrates or fats, as elevated insulin may blunt GH release.
How to Reconstitute and Store CJC-1295 DAC
Reconstitution
Use bacteriostatic water (1–2ml) to reconstitute the 2mg vial
Swirl gently—do not shake—to mix the powder with the water
Storage
Before Reconstitution: Store in a cool, dry place or refrigerate at 2–8°C
After Reconstitution: Keep refrigerated (2–8°C) and use within 20–30 days
Avoid repeated temperature fluctuations and always store away from direct sunlight
Who is CJC-1295 DAC Suitable For?
CJC-1295 DAC may be beneficial for:
✅ Bodybuilders and athletes – seeking improved muscle growth, recovery, and fat loss
✅ Aging individuals – looking to boost vitality, improve skin health, and enhance sleep
✅ Biohackers and longevity enthusiasts – for GH-related anti-aging effects
✅ People recovering from injury – due to its tissue regeneration support
Safety and Potential Side Effects
Although generally well-tolerated, users should be aware of potential side effects:
Water retention
Headaches
Flushing or tingling at the injection site
Numbness in hands or feet (from elevated GH)
Mild nausea or fatigue
It is recommended to consult a medical professional before starting any peptide regimen—especially for those with underlying health issues, diabetes, or cancer history, since GH can potentially accelerate tumour growth.
Scientific Studies and References
Conclusion
CJC-1295 DAC – 2mg is a potent, long-acting peptide that provides a convenient and effective means to enhance growth hormone levels, support lean muscle gains, promote fat loss, and foster anti-aging benefits. With scientific backing and a relatively low frequency of dosing, it has become a popular choice for those seeking performance and wellness enhancement.
As always, responsible use, proper storage, and professional supervision are crucial to maximise benefits while minimising risks.
Citations
CJC-1295: A Drug Affinity Complex-Growth Hormone-Releasing Factor Analog That Increases IGF-I Levels In Humans. Endocrine Reviews – https://doi.org/10.1210/endo-meetings.2006.P2.P2-107 ↩
Veldhuis, J. D., et al. (2005). Physiological regulation of the human growth hormone (GH)–insulin-like growth factor type I axis: predominance of nutritional over hormonal regulation. Journal of Clinical Endocrinology & Metabolism, 90(5), 3054–3061. ↩
Teichman, S. L., et al. (2006). Prolonged stimulation of GH and IGF-1 secretion by CJC-1295, a long-acting GHRH analog. Journal of Clinical Endocrinology & Metabolism, 91(3), 799–805. https://doi.org/10.1210/jc.2005-1536 ↩
Van Cauter, E., & Plat, L. (1996). Physiology of growth hormone secretion during sleep. Journal of Pediatrics, 128(5), S32–S37. ↩